Preheat oven to 375 degrees F.
Line a rimmed baking sheet with aluminum foil or parchment paper and set aside. I recommend using a half sheet pan.
In a small bowl combine the seasonings for the pork; garlic powder, onion powder, salt, black pepper and smoked paprika.
Rub the entire pork loin with spice mixture.
In a frying pan heat 2 Tbsp of olive oil over medium heat. When olive oil is hot place pork loin in pan and sear until all sides are browned; about 2-3 minutes per side.
Transfer pork loin to prepared baking sheet with the fat-layer up.
Place pork loin in preheated oven at 375 degrees F for 25 minutes.
While pork is cooking toss the vegetables along with olive oil and seasonings in a mixing bowl.
Pull pork loin out of oven after 25 minutes and add the vegetables all around it in one layer.
Place pork loin back in oven and cook 25-30 additional minutes or until the internal temperature of the pork loin reaches 145 degrees F.
Remove the baking sheet from the oven and loosely cover with foil. Let rest 3 minutes.
Cut the pork in slices and serve with vegetables.