Preheat the oven to 400 degrees Fahrenheit. Grease a 9x13 inch pan and set aside.
Combine topping ingredients in a small bowl. Set aside.
Cook pasta to al dente according to package directions. Drain and run under cold water and set aside.
While pasta is cooking, melt butter over medium heat in a saucepan. Stir in onion powder, garlic powder, dried mustard, salt, and pepper. Add in flour and whisk to combine it.
Slowly add half and half, then milk while whisking to combine. The mixture will be very thick at first but will smooth out as you continue adding liquid.
Once all of the liquid is added, bring the mixture to a boil. Reduce heat and simmer for 1 to 2 minutes or until thickened while whisking constantly.
Remove from heat and stir in the cheeses, whisking until the sauce is smooth and melted.
Combine the sauce and the pasta. Gently stir in half of the lobster meat.
Pour the mixture into the prepared pan and spread out evenly.
Add remaining lobster meat on top and then sprinkle with the topping mixture.
Bake at 400 degrees Fahrenheit in preheated oven for 18-20 minutes or until bubbly and topping is browned.